AI-Edigene? EGFR VIII (E2-E7del) Translocation
CBP20203D#
詢 價
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫
| Introduction | |
| Format | DNA |
| Description | EGFR (HER1), epidermal growth factor receptor, is a tyrosine kinase receptor, which activates RAS/RAF/MEK and PI3K/AKT/mTOR pathways, leading to increased cell proliferation and growth. EGFR activating mutations, amplification, and overexpression are found in a variety of tumors, including non-small cell lung cancerand colorectal cancer, and the EGFRvIII variant is commonly found in glioblastoma. |
| Technical Data | |
| Left Gene | EGFR（E2） |
| Left Breakpoint | chr7:55206313:+ |
| Right Gene | EGFR（E7） |
| Right Breakpoint | chr7:55223325:+ |
| %AF | 50% |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
