AI-Edigene? FLT3 p.I836del Reference Standard Plus
CBP10525
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產(chǎn)品描述
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| Introduction | |
| Format | Genomic DNA |
| Description |
FLT3 I836del results in the deletion of an amino acid in the protein kinase domain activation loop of the Flt3 protein at amino acid 836 (PMID: 12663439). I836del results in constitutive phosphorylation of Flt3 and activation of Stat5, Erk signaling, leading to transformation of cultured cells (PMID: 15256420).
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| Technical Data | |
| DNA Change | c.2508_2510delCAT |
| AA Change | p.I836del |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_004119.3 |
| Cosmic ID | COSM797 |
| Chr position(GRCh37) | chr13:28592637_28592639 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
